Systems Approach to Innovation Helps Extract More Data

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3 Bullets: Technology lag affects the study of proteins, which when quantified can indicate disease or wellness. ISB uses systems approach to innovate and transcend technology limitations. ISB co-develops new technique and software suite to increase protein detection rate. By Dr. Kristian Swearingen Scientific…

New Study: Blood Test Helps Identify Benign Lung Nodules

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Oct. 16, 2013 When it comes to determining whether lung nodules are benign, a patient typically faces surgery and a biopsy. It's an invasive and costly response, and, in 80 percent of cases, unnecessary. But a new study published today in Science Translational Medicine…

ISB Retreat 2013: Wellness and Community

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“This is the best retreat we’ve ever had – I say that every year. But this was a singular retreat in that it catalyzed an enormously interesting conversation about future opportunities.” – Lee Hood Every September, ISB holds an all-staff overnight retreat to step…

New Open-Access Software Helps Predict Cellular Actions Tied to Diseases, Drug Targets

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All living things are made of cells that contain DNA, which help determine their physical characteristics. In addition to this encoded genetic information, organisms are also defined by the way they decode information from interactions with their environments. Signals from the environment are interpreted…

Luxembourg-ISB Partnership: ‘An Unqualified Success’

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By Hsiao-Ching Chou LUXEMBOURG JOURNAL, June 12, 2013 – At the 17th-century Neumünster Abbey, the cultural heart of Luxembourg City, a small group of some of the world’s most cutting-edge scientists gathered on June 10-11, 2013, for a symposium to discuss the future of…

Some Algae Are Destined to Die for the Good of the Planet

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Researchers at ISB discover that programmed cell death of algae may play an important role in driving the global carbon cycle By ISB News Team May 8, 2013 — Nearly 25 gigatons of carbon is cycled annually through the oceans, replenishing resources for a…

Biggest Family Tree of Human Cells May Help Develop Cell-Replacement Therapies

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Researchers at ISB Curated Existing Data to Create Lineage Map, Develop Open-Access Web Tool to Enable Further Studies By ISB News Team Scientists at Institute for Systems Biology (ISB), University of Luxembourg, and Tampere University of Technology have created a method that identifies the…

Aitchison Group Published in Cell

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[Editor’s Note: ISB and Seattle BioMed have a formal inter-institutional agreement that allows our scientists to share resources and core technologies. It also grows the reach of ISB’s signature cross-disciplinary and integrative collaboration, a necessary aspect of our systems approach. Here, Hannah Krakauer, Seattle...

Only at ISB: Our Proteomics Journey

From left: Senior scientist Eric Deutsch, research scientist Ulrike Kusebauch, and director of proteomics, Dr. Robert Moritz, are pictured in ISB’s mass spectrometry lab, which is the largest on the West Coast. THEN ISB was founded in 2000 by Dr. Lee Hood, a systems…

Combing the Hairball

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Traditional node-link diagram of a network of yeast protein-protein and protein-DNA interactions with over 3,000 nodes and 6,800 links. Data from: von Mering et. al. Nature, 417, 399-403, May 2002; Lee et. al. Science, 298: 799-804 (2002) The node-link diagram above is a “hairball”…